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- 2003 Wolf Prize in Agriculture
Intro
American animal scientist. He was awarded the 2003 Wolf Prize in Agriculture for “discoveries of Interferon tau and other pregnancy-associated proteins, which clarified the biological mystery of signaling between embryo and mother to maintain pregnancy, with profound effects on the efficiency of animal production systems, as well as human health and well-being”.
Education and Work Experience
1969, Ph.D. in Animal Science, North Carolina State University
1992-Present, Joint Appointments in Veterinary Integrative Biosciences and Veterinary Physiology and Pharmacology, Texas A&M University
1992-2001, Director, Center for Animal Biotechnology and Genomics, Texas A&M University
2004-Present, Distinguished University Professor, Department of Animal Science, Texas A&M University
Honors and Awards
1980, American Society of Animal Science Award in Physiology and Endocrinology 1996, Gamma Sigma Delta International Distinguished Achievement Award in Agriculture
2003, Wolf Prize in Agriculture
2010, Pioneer Award of International Society for Ruminant Reproduction
Major Academic Achievements
Fuller Bazer is known for his contributions in the biological mystery of embryo-maternal signaling, that maintain pregnancy and survival of the embryo in livestock species. It was known that chemical communication between embryo and mother was essential for successful pregnancy in mammals. Among his key discoveries, Fuller isolated the uterine protein uteroferrin, a hematopoietic growth factor that influences the survival of
the neonate and may be useful in treating diseases, such as leukemia and osteoporosis. He determined that estrogen in pigs and interferon-t in ruminant species, are the signals for pregnancy maintenance. The ability of interferon-t to suppress transcription of the
estrogen receptor gene, provides a model for potential treatment of estrogen-dependent tumors.